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symbol A has been deleted is made and G is then matched to M2. C is matched to M3. Finally, the fourth sequence AGC matches all three match states Figure 4.6(b). The HMM construction is now complete, with all occurrences of symbols observed. The nal and full HMM is given in Figure 4.7. After the nal sequence is fed through the HMM, the construction is complete and all probabilities are output together with the HMM (Figure 4.7). At the top left of Figure 4.7 are the four sequences, together with the possible multiple alignment that identi es the consensus AGC. Below each match state M1, M2 and M3 in the HMM are the consensus symbols (with high probability), with token probabilities attached to other symbols not encountered as a consensus. To the left are the insertion probabilities for each insert state. Since I0 is entered twice (for CAGC and TGC), C and T have probabilities close to 0.5 (0.45), with token probabilities attached to the other symbols (X signi es any other symbol). 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One criticism of this perspective is that it emphasizes a human interventionist perspective it is overly human centered, neglecting to consider causes that cannot be manipulated, such as naturally occurring events (e.g., the earthquake caused the building to collapse), causes that represent xed attributes of an object (her fair skin caused her to burn easily) or causes that represent environmental or external conditions beyond the control of humans (increased consumer con dence led to a rally in the stock market). Perhaps one way to resolve this issue is to view causal statements in the context of a counterfactual statement instead, rather than as causes to be manipulated. For example, the causal statement, the earthquake caused the building to collapse can be viewed as the counterfactual statement if the earthquake hadn t occurred, the building wouldn t have collapsed. Let us now explore some examples of causal diagrams. 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